Conditional Ablation of the Choroideremia Gene Causes Age-Related Changes in Mouse Retinal Pigment Epithelium

The retinal pigment epithelium (RPE) is a pigmented monolayer of cells lying between the photoreceptors and a layer of fenestrated capillaries, the choriocapillaris. Choroideremia (CHM) is an X-linked progressive degeneration of these three layers caused by the loss of function of Rab Escort protein...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wavre-Shapton, Silène T., Tolmachova, Tanya, da Silva, Mafalda Lopes, Futter, Clare E., Seabra, Miguel C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584022/
https://ncbi.nlm.nih.gov/pubmed/23460904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057769
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