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Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function.

AU-rich elements (ARE) in the 3' untranslated region of many highly labile mRNAs for proto-oncogenes, lymphokines, and cytokines can act as an RNA-destabilizing element. The absence of a clear understanding of the key sequence and structural features of the ARE that are required for its destabilizin...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Chen, C Y, Chen, T M, Shyu, A B
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7903419/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.416-426.1994
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