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Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment.

Mice lacking c-fos develop severe osteopetrosis with deficiencies in bone remodeling and exhibit extramedullary hematopoiesis, thymic atrophy, and altered B-cell development. In this study, we have used these mice to characterize in detail the developmental potential of hematopoietic stem cells lack...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Okada, S, Wang, Z Q, Grigoriadis, A E, Wagner, E F, von Rüden, T
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358387/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264605/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.382
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