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Novel upstream and downstream sequence elements contribute to polyadenylation efficiency

Polyadenylation is a 3′ mRNA processing event that contributes to gene expression by affecting stability, export and translation of mRNA. Human polyadenylation signals (PAS) have core and auxiliary elements that bind polyadenylation factors upstream and downstream of the cleavage site. The majority...

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Hlavní autoři: Darmon, Sarah K., Lutz, Carol S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583856/
https://ncbi.nlm.nih.gov/pubmed/23085579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21957
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