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Novel upstream and downstream sequence elements contribute to polyadenylation efficiency

Polyadenylation is a 3′ mRNA processing event that contributes to gene expression by affecting stability, export and translation of mRNA. Human polyadenylation signals (PAS) have core and auxiliary elements that bind polyadenylation factors upstream and downstream of the cleavage site. The majority...

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Detalhes bibliográficos
Main Authors: Darmon, Sarah K., Lutz, Carol S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583856/
https://ncbi.nlm.nih.gov/pubmed/23085579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21957
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