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Correlation of MLH1 and MGMT expression and promoter methylation with genomic instability in patients with thyroid carcinoma

BACKGROUND: Gene silencing of the repair genes MLH1 and MGMT was shown to be a mechanism underlying the development of microsatellite instability (MSI), a phenotype frequently associated with various human malignancies. Recently, aberrant methylation of MLH1, MGMT and MSI were shown to be associated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Santos, Juliana Carvalho, Bastos, André Uchimura, Cerutti, Janete Maria, Ribeiro, Marcelo Lima
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583824/
https://ncbi.nlm.nih.gov/pubmed/23414134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-79
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