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Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development
BACKGROUND: With the increasing resistance of malaria parasites to available drugs, there is an urgent demand to develop new anti-malarial drugs. Calpain inhibitor, ALLN, is proposed to inhibit parasite proliferation by suppressing haemoglobin degradation. This provides Plasmodium calpain as a poten...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583800/ https://ncbi.nlm.nih.gov/pubmed/23374507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-47 |
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