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Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

Glioblastoma multiforme is the most common primary brain tumor and one of the most aggressive types of cancer in adults. Survival signaling and apoptosis resistance are hallmarks of malignant glioma cells. However, recent studies have shown that other types of cell death such as autophagy can be ind...

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Main Authors: OLSEN, BIRGITTE B., SVENSTRUP, TINA H., GUERRA, BARBARA
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583692/
https://ncbi.nlm.nih.gov/pubmed/23007634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1635
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