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Silencing of the hTERT gene through RNA interference induces apoptosis via Bax/Bcl-2 in human glioma cells

Glioma cells are characterized by their invasiveness and resistance to conventional therapeutics. The downregulation of human telomerase reverse transcriptase (hTERT) can lead to decreased cell proliferation and/or the induction of apoptotic cell death in cancer cells but has rarely been reported in...

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Autors principals: WANG, TUO, XUE, YAN, WANG, MAODE, SUN, QIANG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583528/
https://ncbi.nlm.nih.gov/pubmed/22895663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1952
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