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Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

N(1),N(11)-diethylnorspermine (DENSPM), a polyamine analog that induces expression of spermidine/spermine N(1)-acetyltransferase (SSAT) and reduces polyamine levels in eukaryotic cells, has demonstrated anticancer effects in many cancer cell types. Gene expression of SSAT after treatment with DENSPM...

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Bibliografiske detaljer
Main Authors: TIAN, YE, WANG, SHIZHAO, WANG, BIN, ZHANG, JIANNING, JIANG, RONGCAI, ZHANG, WEI
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583519/
https://ncbi.nlm.nih.gov/pubmed/22179681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2011.1592
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