Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease

The UDP-glucuronosyltransferases (UGTs) and sulfotransferases (SULTs) represent major phase II drug-metabolizing enzymes that are also responsible for maintaining cellular homeostasis by metabolism of several endogenous molecules. Perturbations in the expression or function of these enzymes can lead...

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Hauptverfasser: Hardwick, Rhiannon N., Ferreira, Daniel W., More, Vijay R., Lake, April D., Lu, Zhenqiang, Manautou, Jose E., Slitt, Angela L., Cherrington, Nathan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583487/
https://ncbi.nlm.nih.gov/pubmed/23223517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.048439
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