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Computationally Assisted Assignment of Kahalalide Y Configuration Using an NMR-Constrained Conformational Search

Assignment of the absolute configuration of cyclic peptides frequently yields challenges, leaving one or more stereogenic centers unassigned due to small quantities of sample and the limited utility of Marfey’s or other methods for assigning amino or hydroxy acids. Here, we report isolation of kahal...

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Autori principali: Albadry, Mohamed A., Elokely, Khaled M., Wang, Bin, Bowling, John J., Abdelwahab, Mohamed F., Hossein, Mohamed H., Doerksen, Robert J., Hamann, Mark T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583380/
https://ncbi.nlm.nih.gov/pubmed/23363083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np3006088
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