Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

AIMS: Elevated levels of pro-inflammatory cytokine interleukin-17A (IL-17) are associated with hypertensive autoimmune diseases; however, the connection between IL-17 and hypertension is unknown. We hypothesized that IL-17 increases blood pressure by decreasing endothelial nitric oxide production. M...

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Bibliographic Details
Main Authors: Nguyen, Hoanglan, Chiasson, Valorie L., Chatterjee, Piyali, Kopriva, Shelley E., Young, Kristina J., Mitchell, Brett M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583258/
https://ncbi.nlm.nih.gov/pubmed/23263331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs422
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