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Pin1 Deficiency Causes Endothelial Dysfunction and Hypertension

Pin1 is a peptidyl prolyl cis-trans isomerase that only binds to and isomerizes phosphorylated serine/threonine-proline motifs, inducing conformational changes that alter target protein function and phosphorylation. We have shown previously that deficiency of another peptidyl prolyl isomerase, FK506...

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Detalhes bibliográficos
Main Authors: Chiasson, Valorie L., Munshi, Nidhi, Chatterjee, Piyali, Young, Kristina J., Mitchell, Brett M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096767/
https://ncbi.nlm.nih.gov/pubmed/21810655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.172338
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