Linoleic acid metabolite drives severe asthma by causing airway epithelial injury

Airway epithelial injury is the hallmark of various respiratory diseases, but its mechanisms remain poorly understood. While 13-S-hydroxyoctadecadienoic acid (13-S-HODE) is produced in high concentration during mitochondrial degradation in reticulocytes little is known about its role in asthma patho...

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Autors principals: Mabalirajan, Ulaganathan, Rehman, Rakhshinda, Ahmad, Tanveer, Kumar, Sarvesh, Singh, Suchita, Leishangthem, Geeta D., Aich, Jyotirmoi, Kumar, Manish, Khanna, Kritika, Singh, Vijay P., Dinda, Amit K., Biswal, Shyam, Agrawal, Anurag, Ghosh, Balaram
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583002/
https://ncbi.nlm.nih.gov/pubmed/23443229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01349
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