Epimutation and cancer: A new carcinogenic mechanism of Lynch syndrome

Epimutation is defined as abnormal transcriptional repression of active genes and/or abnormal activation of usually repressed genes caused by errors in epigenetic gene repression. Epimutation arises in somatic cells and the germline, and constitutional epimutation may also occur. Epimutation is the...

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Bibliografiske detaljer
Main Authors: BANNO, KOUJI, KISU, IORI, YANOKURA, MEGUMI, TSUJI, KOSUKE, MASUDA, KENTA, UEKI, ARISA, KOBAYASHI, YUSUKE, YAMAGAMI, WATARU, NOMURA, HIROYUKI, TOMINAGA, EIICHIRO, SUSUMU, NOBUYUKI, AOKI, DAISUKE
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2012
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582986/
https://ncbi.nlm.nih.gov/pubmed/22735547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1528
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