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Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination
Cytochrome c is a highly conserved protein, with 20 residues identical in all eukaryotic cytochromes c. Glycine 41 is one of these invariant residues, and is the position of the only reported naturally occurring mutation in cytochrome c (human G41S). The basis, if any, for the conservation of Gly-41...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582831/ https://ncbi.nlm.nih.gov/pubmed/23334161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-012-0973-1 |
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