Design, Synthesis and Biological Evaluation of Sulfur-Containing 1,1-Bisphosphonic Acids as Antiparasitic Agents

As part of our efforts aimed at searching for new antiparasitic agents, 2-alkylmercaptoethyl-1,1-bisphosphonate derivatives were synthesized and evaluated against Trypanosoma cruzi, the etiologic agent of Chagas disease, and Toxoplasma gondii, the responsible agent for toxoplasmosis. Many of these s...

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Главные авторы: Recher, Marion, Barboza, Alejandro P., Li, Zhu-Hong, Galizzi, Melina, Ferrer-Casal, Mariana, Szajnman, Sergio H., Docampo, Roberto, Moreno, Silvia N. J., Rodriguez, Juan B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582829/
https://ncbi.nlm.nih.gov/pubmed/23318904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.12.015
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