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Alfentanil: Correlations Between Absence of Effect Upon Subcutaneous Mast Cells and Absence of Granuloma Formation After Intrathecal Infusion in the Dog

BACKGROUND: We hypothesize that intrathecal (IT) granulomas arising from the IT infusion of several opiates may result from the degranulation of meningeal mast cells (MC). Given functional covariance between cutaneous and meningeal mast cells, we propose that opioids that do not degranulate cutaneou...

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Autori principali: Yaksh, Tony L., Steinauer, Joanne J., Williams, Samantha L., Malkmus, Shelle A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582801/
https://ncbi.nlm.nih.gov/pubmed/23170763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1525-1403.2012.00534.x
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