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High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels

Specific members of the inward rectifier potassium (Kir) channel family are postulated drug targets for a variety of disorders, including hypertension, atrial fibrillation, and pain(1,2). For the most part, however, progress toward understanding their therapeutic potential or even basic physiologica...

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Autori principali: Raphemot, Rene, Weaver, C. David, Denton, Jerod S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582647/
https://ncbi.nlm.nih.gov/pubmed/23381507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4209
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