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A20: linking a complex regulator of ubiquitylation to immunity and human disease

A20 (also known as TNFAIP3) is a potent anti-inflammatory signalling molecule that restricts multiple intracellular signalling cascades. Recent studies in three general areas have converged to highlight the clinical and biological importance of A20. First, human genetic studies have strongly linked...

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Detalhes bibliográficos
Main Authors: Ma, Averil, Malynn, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582397/
https://ncbi.nlm.nih.gov/pubmed/23059429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3313
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