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A20: linking a complex regulator of ubiquitylation to immunity and human disease
A20 (also known as TNFAIP3) is a potent anti-inflammatory signalling molecule that restricts multiple intracellular signalling cascades. Recent studies in three general areas have converged to highlight the clinical and biological importance of A20. First, human genetic studies have strongly linked...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582397/ https://ncbi.nlm.nih.gov/pubmed/23059429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3313 |
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