Sporadic Obstructive Hydrocephalus in Aqp4 Null Mice

Aquaporin-4 (Aqp4) is a water transport protein expressed in glia and ependymocytes in brain. We report here the unexpected occurrence of severe obstructive hydrocephalus in a random subset of Aqp4 knockout mice. Of 612 Aqp4 knockout mice produced by heterozygote–heterozygote or knockout–knockout br...

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Autors principals: Feng, Xuechao, Papadopoulos, Marios C., Liu, Jun, Li, Lihua, Zhang, Di, Zhang, Hongguo, Verkman, A. S., Ma, Tonghui
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582395/
https://ncbi.nlm.nih.gov/pubmed/18951529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21927
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