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Enhanced Autophagy in Polycystic Kidneys of AQP11 Null Mice

Aquaporin-11 (AQP11) is an intracellular water channel expressed at the endoplasmic reticulum (ER) of the proximal tubule. Its gene disruption in mice leads to intracellular vacuole formation at one week and the subsequent development of polycystic kidneys by three weeks. As the damaged proximal tub...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Tanaka, Yasuko, Watari, Mayumi, Saito, Tatsuya, Morishita, Yoshiyuki, Ishibashi, Kenichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187793/
https://ncbi.nlm.nih.gov/pubmed/27916883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17121993
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