An equilibrium-dependent retroviral mRNA switch regulates translational recoding

Most retroviruses require translational recoding of a viral messenger RNA stop codon to maintain a precise ratio of structural (Gag) and enzymatic (Pol) proteins during virus assembly(1,2). Pol is expressed exclusively as a Gag–Pol fusion either by ribosomal frameshifting or by read-through of the g...

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Bibliographic Details
Main Authors: Houck-Loomis, Brian, Durney, Michael A., Salguero, Carolina, Shankar, Neelaabh, Nagle, Julia M., Goff, Stephen P., D’Souza, Victoria M.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582340/
https://ncbi.nlm.nih.gov/pubmed/22121021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10657
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