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Endogenous production of fibronectin is required for self-renewal of cultured mouse embryonic stem cells
Pluripotent cells are attached to the extracellular matrix (ECM) as they make cell fate decisions within the stem cell niche. Here we show that the ubiquitous ECM protein fibronectin is required for self-renewal decisions by cultured mouse embryonic stem (mES) cells. Undifferentiated mES cells produ...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582329/ https://ncbi.nlm.nih.gov/pubmed/22710062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.06.009 |
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