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Trade-Off in the Effect of the APOE Gene on the Ages at Onset of Cardiocascular Disease and Cancer across Ages, Gender, and Human Generations(*)

Decades of studies of candidate genes show their complex role in aging-related traits. We focus on apolipoprotein E e2/3/4 polymorphism and ages at onset of cardiovascular diseases (CVD) and cancer in the parental and offspring generations of the Framingham Heart Study participants to gain insights...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kulminski, Alexander M., Culminskaya, Irina, Arbeev, Konstantin G., Ukraintseva, Svetlana V., Arbeeva, Liubov, Yashin, Anatoli I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582279/
https://ncbi.nlm.nih.gov/pubmed/23094790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2012.1362
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