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Linkage Disequilibrium and Haplotype Analysis of the ATP7B Gene in Alzheimer's Disease

Copper dyshomeostasis leading to a labile Cu(2+) not bound to ceruloplasmin (“free” copper) may influence Alzheimer's disease (AD) onset or progression. To investigate this hypothesis, we investigated ATP7B, the gene that controls copper excretion through the bile and concentrations of free cop...

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Hlavní autoři: Squitti, Rosanna, Polimanti, Renato, Bucossi, Serena, Ventriglia, Mariacarla, Mariani, Stefania, Manfellotto, Dario, Vernieri, Fabrizio, Cassetta, Emanuele, Ursini, Francesca, Rossini, Paolo Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582274/
https://ncbi.nlm.nih.gov/pubmed/22950421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2012.1357
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