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The HLA-DRB1*15:01–Restricted Goodpasture’s T Cell Epitope Induces GN
Human anti-glomerular basement membrane (GBM) disease strongly associates with HLA-DRB1*15:01. The target autoantigen in this disease is the noncollagenous domain of the α3 chain of type IV collagen, α3(IV)NC1, but critical early T cell epitopes presented by this human MHC class II molecule are unkn...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Nephrology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582203/ https://ncbi.nlm.nih.gov/pubmed/23411782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012070705 |
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