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Depletion of FOXP3(+) regulatory T cells promotes hypercholesterolemia and atherosclerosis

Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; however, the mechanism underlying this protection remains elusive. To define the role of FOXP3-expressing Tregs in atheros...

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Detalhes bibliográficos
Main Authors: Klingenberg, Roland, Gerdes, Norbert, Badeau, Robert M., Gisterå, Anton, Strodthoff, Daniela, Ketelhuth, Daniel F.J., Lundberg, Anna M., Rudling, Mats, Nilsson, Stefan K., Olivecrona, Gunilla, Zoller, Stefan, Lohmann, Christine, Lüscher, Thomas F., Jauhiainen, Matti, Sparwasser, Tim, Hansson, Göran K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582120/
https://ncbi.nlm.nih.gov/pubmed/23426179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63891
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