Depletion of FOXP3(+) regulatory T cells promotes hypercholesterolemia and atherosclerosis

Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; however, the mechanism underlying this protection remains elusive. To define the role of FOXP3-expressing Tregs in atheros...

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Autors principals: Klingenberg, Roland, Gerdes, Norbert, Badeau, Robert M., Gisterå, Anton, Strodthoff, Daniela, Ketelhuth, Daniel F.J., Lundberg, Anna M., Rudling, Mats, Nilsson, Stefan K., Olivecrona, Gunilla, Zoller, Stefan, Lohmann, Christine, Lüscher, Thomas F., Jauhiainen, Matti, Sparwasser, Tim, Hansson, Göran K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582120/
https://ncbi.nlm.nih.gov/pubmed/23426179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63891
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