IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver

In the tumor microenvironment, TGF-β induces transdifferentiation of quiescent pericytes and related stromal cells into myofibroblasts that promote tumor growth and metastasis. The mechanisms governing myofibroblastic activation remain poorly understood, and its role in the tumor microenvironment ha...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Chunsheng, Billadeau, Daniel D., Abdelhakim, Haitham, Leof, Edward, Kaibuchi, Kozo, Bernabeu, Carmelo, Bloom, George S., Yang, Liu, Boardman, Lisa, Shah, Vijay H., Kang, Ningling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582119/
https://ncbi.nlm.nih.gov/pubmed/23454766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63836
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