HDAC4 controls histone methylation in response to elevated cardiac load

In patients with heart failure, reactivation of a fetal gene program, including atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), is a hallmark for maladaptive remodeling of the LV. The mechanisms that regulate this reactivation are incompletely understood. Histone acetylation an...

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Autores principales: Hohl, Mathias, Wagner, Michael, Reil, Jan-Christian, Müller, Sarah-Anne, Tauchnitz, Marcus, Zimmer, Angela M., Lehmann, Lorenz H., Thiel, Gerald, Böhm, Michael, Backs, Johannes, Maack, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582114/
https://ncbi.nlm.nih.gov/pubmed/23434587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61084
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