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Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal

Legionella and Coxiella are intracellular pathogens that use the virulence-related Icm/Dot type-IVB secretion system to translocate effector proteins into host cells during infection. These effectors were previously shown to contain a C-terminal secretion signal required for their translocation. In...

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Autores principales: Lifshitz, Ziv, Burstein, David, Peeri, Michael, Zusman, Tal, Schwartz, Kierstyn, Shuman, Howard A., Pupko, Tal, Segal, Gil
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581968/
https://ncbi.nlm.nih.gov/pubmed/23382224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215278110
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