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Intricate interplay between astrocytes and motor neurons in ALS

ALS results from the selective and progressive degeneration of motor neurons. Although the underlying disease mechanisms remain unknown, glial cells have been implicated in ALS disease progression. Here, we examine the effects of glial cell/motor neuron interactions on gene expression using the hSOD...

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Détails bibliographiques
Auteurs principaux: Phatnani, Hemali P., Guarnieri, Paolo, Friedman, Brad A., Carrasco, Monica A., Muratet, Michael, O’Keeffe, Sean, Nwakeze, Chiamaka, Pauli-Behn, Florencia, Newberry, Kimberly M., Meadows, Sarah K., Tapia, Juan Carlos, Myers, Richard M., Maniatis, Tom
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581928/
https://ncbi.nlm.nih.gov/pubmed/23388633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222361110
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