Intricate interplay between astrocytes and motor neurons in ALS

ALS results from the selective and progressive degeneration of motor neurons. Although the underlying disease mechanisms remain unknown, glial cells have been implicated in ALS disease progression. Here, we examine the effects of glial cell/motor neuron interactions on gene expression using the hSOD...

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Hlavní autoři: Phatnani, Hemali P., Guarnieri, Paolo, Friedman, Brad A., Carrasco, Monica A., Muratet, Michael, O’Keeffe, Sean, Nwakeze, Chiamaka, Pauli-Behn, Florencia, Newberry, Kimberly M., Meadows, Sarah K., Tapia, Juan Carlos, Myers, Richard M., Maniatis, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581928/
https://ncbi.nlm.nih.gov/pubmed/23388633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222361110
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