Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells

The derivation of induced pluripotent stem (iPS) cells from individuals of genetic disorders offers new opportunities for basic research into these diseases and the development of therapeutic compounds. Severe congenital neutropenia (SCN) is a serious disorder characterized by severe neutropenia at...

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Main Authors: Hiramoto, Takafumi, Ebihara, Yasuhiro, Mizoguchi, Yoko, Nakamura, Kazuhiro, Yamaguchi, Kiyoshi, Ueno, Kazuko, Nariai, Naoki, Mochizuki, Shinji, Yamamoto, Shohei, Nagasaki, Masao, Furukawa, Yoichi, Tani, Kenzaburo, Nakauchi, Hiromitsu, Kobayashi, Masao, Tsuji, Kohichiro
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581925/
https://ncbi.nlm.nih.gov/pubmed/23382209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217039110
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