Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells

The derivation of induced pluripotent stem (iPS) cells from individuals of genetic disorders offers new opportunities for basic research into these diseases and the development of therapeutic compounds. Severe congenital neutropenia (SCN) is a serious disorder characterized by severe neutropenia at...

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Hlavní autoři: Hiramoto, Takafumi, Ebihara, Yasuhiro, Mizoguchi, Yoko, Nakamura, Kazuhiro, Yamaguchi, Kiyoshi, Ueno, Kazuko, Nariai, Naoki, Mochizuki, Shinji, Yamamoto, Shohei, Nagasaki, Masao, Furukawa, Yoichi, Tani, Kenzaburo, Nakauchi, Hiromitsu, Kobayashi, Masao, Tsuji, Kohichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581925/
https://ncbi.nlm.nih.gov/pubmed/23382209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217039110
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