Investigating Gabapentin Polymorphism Using Solid-State NMR Spectroscopy

Solid-state NMR spectroscopy (SSNMR), coupled with powder X-ray diffraction (PXRD), was used to identify the physical forms of gabapentin in samples prepared by recrystallization, spray drying, dehydration, and milling. Four different crystalline forms of gabapentin were observed: form I, a monohydr...

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Main Authors: Dempah, Kassibla E., Barich, Dewey H., Kaushal, Aditya M., Zong, Zhixin, Desai, Salil D., Suryanarayanan, Raj, Kirsch, Lee, Munson, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581669/
https://ncbi.nlm.nih.gov/pubmed/23180225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9879-z
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