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Thermally Triggered Mucoadhesive In Situ Gel of Loratadine: β-Cyclodextrin Complex for Nasal Delivery
The aim of the present study was to increase the solubility of an anti-allergic drug loratadine by making its inclusion complex with β-cyclodextrin and to develop it’s thermally triggered mucoadhesive in situ nasal gel so as to overcome first-pass effect and consequently enhance its bioavailability....
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581637/ https://ncbi.nlm.nih.gov/pubmed/23358934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-9921-9 |
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