Ca(2+)/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity and Sinoatrial Nodal Pacemaker Cell Energetics

Ca(2+)-activated basal adenylate cyclase (AC) in rabbit sinoatrial node cells (SANC) guarantees, via basal cAMP/PKA-calmodulin/CaMKII-dependent protein phosphorylation, the occurrence of rhythmic, sarcoplasmic-reticulum generated, sub-membrane Ca(2+) releases that prompt rhythmic, spontaneous action...

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Main Authors: Yaniv, Yael, Spurgeon, Harold A., Ziman, Bruce D., Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581576/
https://ncbi.nlm.nih.gov/pubmed/23459256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057079
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