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The Impact of Gene Duplication, Insertion, Deletion, Lateral Gene Transfer and Sequencing Error on Orthology Inference: A Simulation Study

The identification of orthologous genes, a prerequisite for numerous analyses in comparative and functional genomics, is commonly performed computationally from protein sequences. Several previous studies have compared the accuracy of orthology inference methods, but simulated data has not typically...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dalquen, Daniel A., Altenhoff, Adrian M., Gonnet, Gaston H., Dessimoz, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581572/
https://ncbi.nlm.nih.gov/pubmed/23451112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056925
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