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The Impact of Gene Duplication, Insertion, Deletion, Lateral Gene Transfer and Sequencing Error on Orthology Inference: A Simulation Study

The identification of orthologous genes, a prerequisite for numerous analyses in comparative and functional genomics, is commonly performed computationally from protein sequences. Several previous studies have compared the accuracy of orthology inference methods, but simulated data has not typically...

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Bibliografiske detaljer
Main Authors: Dalquen, Daniel A., Altenhoff, Adrian M., Gonnet, Gaston H., Dessimoz, Christophe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581572/
https://ncbi.nlm.nih.gov/pubmed/23451112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056925
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