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Suppression of the Macrophage Proteasome by Ethanol Impairs MHC Class I Antigen Processing and Presentation

Alcohol binge-drinking (acute ethanol consumption) is immunosuppressive and alters both the innate and adaptive arms of the immune system. Antigen presentation by macrophages (and other antigen presenting cells) represents an important function of the innate immune system that, in part, determines t...

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Detalhes bibliográficos
Main Authors: D’Souza, Alain J., Desai, Shyamal D., Rudner, Xiaowen L., Kelly, Michelle N., Ruan, SanBao, Shellito, Judd E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581560/
https://ncbi.nlm.nih.gov/pubmed/23451104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056890
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