SGLT5 Reabsorbs Fructose in the Kidney but Its Deficiency Paradoxically Exacerbates Hepatic Steatosis Induced by Fructose

Although excessive fructose intake is epidemiologically linked with dyslipidemia, obesity, and diabetes, the mechanisms regulating plasma fructose are not well known. Cells transfected with sodium/glucose cotransporter 5 (SGLT5), which is expressed exclusively in the kidney, transport fructose in vi...

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Main Authors: Fukuzawa, Taku, Fukazawa, Masanori, Ueda, Otoya, Shimada, Hideaki, Kito, Aki, Kakefuda, Mami, Kawase, Yosuke, Wada, Naoko A., Goto, Chisato, Fukushima, Naoshi, Jishage, Kou-ichi, Honda, Kiyofumi, King, George L., Kawabe, Yoshiki
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581502/
https://ncbi.nlm.nih.gov/pubmed/23451068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056681
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