Dexamethasone Attenuates VEGF Expression and Inflammation but Not Barrier Dysfunction in a Murine Model of Ventilator–Induced Lung Injury

BACKGROUND: Ventilator–induced lung injury (VILI) is characterized by vascular leakage and inflammatory responses eventually leading to pulmonary dysfunction. Vascular endothelial growth factor (VEGF) has been proposed to be involved in the pathogenesis of VILI. This study examines the inhibitory ef...

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Main Authors: Hegeman, Maria A., Hennus, Marije P., Cobelens, Pieter M., Kavelaars, Annemieke, Jansen, Nicolaas J. G., Schultz, Marcus J., van Vught, Adrianus J., Heijnen, Cobi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581459/
https://ncbi.nlm.nih.gov/pubmed/23451215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057374
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