Dexamethasone Attenuates VEGF Expression and Inflammation but Not Barrier Dysfunction in a Murine Model of Ventilator–Induced Lung Injury

BACKGROUND: Ventilator–induced lung injury (VILI) is characterized by vascular leakage and inflammatory responses eventually leading to pulmonary dysfunction. Vascular endothelial growth factor (VEGF) has been proposed to be involved in the pathogenesis of VILI. This study examines the inhibitory ef...

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Autors principals: Hegeman, Maria A., Hennus, Marije P., Cobelens, Pieter M., Kavelaars, Annemieke, Jansen, Nicolaas J. G., Schultz, Marcus J., van Vught, Adrianus J., Heijnen, Cobi J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581459/
https://ncbi.nlm.nih.gov/pubmed/23451215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057374
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