Angiopoietin-1 Treatment Reduces Inflammation but Does Not Prevent Ventilator-Induced Lung Injury

BACKGROUND: Loss of integrity of the epithelial and endothelial barriers is thought to be a prominent feature of ventilator-induced lung injury (VILI). Based on its function in vascular integrity, we hypothesize that the angiopoietin (Ang)-Tie2 system plays a role in the development of VILI. The pre...

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Detalhes bibliográficos
Main Authors: Hegeman, Maria A., Hennus, Marije P., van Meurs, Matijs, Cobelens, Pieter M., Kavelaars, Annemieke, Jansen, Nicolaas J., Schultz, Marcus J., van Vught, Adrianus J., Molema, Grietje, Heijnen, Cobi J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001877/
https://ncbi.nlm.nih.gov/pubmed/21179479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015653
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