Nuclear Import and Export Signals Control the Subcellular Localization of Nurr1 Protein in Response to Oxidative Stress

Orphan receptor Nurr1 participates in the acquisition and maintenance of the dopaminergic cell phenotype, modulation of inflammation, and cytoprotection, but little is known about its regulation. In this study, we report that Nurr1 contains a bipartite nuclear localization signal (NLS) within its DN...

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Bibliographic Details
Main Authors: García-Yagüe, Ángel Juan, Rada, Patricia, Rojo, Ana I., Lastres-Becker, Isabel, Cuadrado, Antonio
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581400/
https://ncbi.nlm.nih.gov/pubmed/23283970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.439190
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