Recruitment of Histone Methyltransferase G9a Mediates Transcriptional Repression of Fgf21 Gene by E4BP4 Protein

The liver responds to fasting-refeeding cycles by reprogramming expression of metabolic genes. Fasting potently induces one of the key hepatic hormones, fibroblast growth factor 21 (FGF21), to promote lipolysis, fatty acid oxidation, and ketogenesis, whereas refeeding suppresses its expression. We p...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tong, Xin, Zhang, Deqiang, Buelow, Katie, Guha, Anirvan, Arthurs, Blake, Brady, Hugh J. M., Yin, Lei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581381/
https://ncbi.nlm.nih.gov/pubmed/23283977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433482
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