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New aspects of the phosphatase VHZ revealed by a high-resolution structure with vanadate and substrate screening

The recently discovered 150-residue human VHZ (VH1 related protein, Z member) is one of the smallest protein tyrosine phosphatases (PTPs) known, and contains only the minimal structural elements common to all PTPs. We report a substrate screening analysis and a crystal structure of the VHZ complex w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kuznetsov, Vyacheslav I., Hengge, Alvan C., Johnson, Sean J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581349/
https://ncbi.nlm.nih.gov/pubmed/23145819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300908y
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