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New aspects of the phosphatase VHZ revealed by a high-resolution structure with vanadate and substrate screening
The recently discovered 150-residue human VHZ (VH1 related protein, Z member) is one of the smallest protein tyrosine phosphatases (PTPs) known, and contains only the minimal structural elements common to all PTPs. We report a substrate screening analysis and a crystal structure of the VHZ complex w...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581349/ https://ncbi.nlm.nih.gov/pubmed/23145819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300908y |
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